## The American Statistical Association Says [Mostly] No to p-values

Norman Matloff has published a new post after receiving criticism and comments about stating “The ASA says No to p-values” in his post I wrote about yesterday. He defends his interpretation in this new post. However, I think, the interpretation of  the statement in a context different from the “Big data” field to which he is used to does not need to always be “Says No to p-values” but instead in many cases could be “Use p-values to assess the strength of the evidence and nothing else”.  However, “tests” with binary outcomes on probabilities that are essentially continuous, will always be based on an arbitrary threshold and discard a great deal of information. Consequently to me using as suggested by Norman Matloff  “assess” in place of “test” makes a lot of sense.

## The American Statistical Association Says No to p-values

Norman Matloff (2016) writes in his post:

Sadly, the concept of p-values and significance testing forms the very core of statistics. A number of us have been pointing out for decades that p-values are at best underinformative and often misleading…

Yesterday, the statement by the American Statistics Association was published on-line in the journal “The American Statistician”. Many statisticians have been aware of the problems of significance tests for a long time, but general practice, teaching and journal instructions and editors’  requirements had not changed. Let’s hope the statement will start real changes in everyday practice.

John W. Tukey (1991) has earlier written quite boldly about the problem:

Statisticians classically asked the wrong question—and were willing to answer with a lie, one that was often a downright lie. They asked “Are the effects of A and B different?” and they were willing to answer “no.”

All we know about the world teaches us that the effects of A and B are always different—in some decimal place—for any A and B. Thus asking the effects different?” is foolish.

What we should be answering first is ”Can we tell the direction in which the effects of A differ from the effects of B?” In other words, can we be confident about the direction from A to B? Is it “up,” “down” or “uncertain”?

The third answer to this first question is that we are “uncertain
about the direction”—it is not, and never should be, that we
“accept the null hypothesis.”

## Bioinformatics error responsible for (retraction) erratum in Science

Update: sorry, my mistake, the paper has not been retracted, an Erratum has been issued If you follow the same kind of feeds and blogs that I do, you can’t have missed the recent retraction i…

Check this very brief post that gives very good advice for any kind of research…

The erratum gives some details. According to a note in Nature the full correction will probably be published at a later time in Science.

## Rigor and Reproducibility

The NIH (USA, National Institutes of Health) has opened a new web site on the subject, which although focused on Biomedical research, provides a good account of current trends and problems, how to overcome them and guidelines that could be easily adapted for the rest of the Biosciences including Plant Science.